Senior Researcher
Address
Ruhr-Universität Bochum
Fakultät für Elektrotechnik und Informationstechnik
Biomedizinsch Angewandte Plasmatechnik
Universitätsstraße 150
D-44801 Bochum, Germany
Room
ID 1/539
Phone
+49 234 32 27670
Email
fuchs(at)aept.rub.de
Publikationen
2825793
Fuchs
apa
50
date
desc
year
1
Fuchs
475
https://www.aept.ruhr-uni-bochum.de/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-b9d91a2c4b518c262b3bbb380935958b%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22GEYE9YQG%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fuchs%20et%20al.%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20F.%2C%20Bibinov%2C%20N.%2C%20Blanco%2C%20E.%20V.%2C%20Pfaender%2C%20S.%2C%20Thei%26%23xDF%3B%2C%20S.%2C%20Wolter%2C%20H.%2C%20%26amp%3B%20Awakowicz%2C%20P.%20%282022%29.%20Characterization%20of%20a%20robot-assisted%20UV-C%20disinfection%20for%20the%20inactivation%20of%20surface-associated%20microorganisms%20and%20viruses.%20%3Ci%3EJournal%20of%20Photochemistry%20and%20Photobiology%3C%5C%2Fi%3E%2C%20%3Ci%3E11%3C%5C%2Fi%3E%2C%20100123.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jpap.2022.100123%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jpap.2022.100123%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DGEYE9YQG%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Characterization%20of%20a%20robot-assisted%20UV-C%20disinfection%20for%20the%20inactivation%20of%20surface-associated%20microorganisms%20and%20viruses%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Felix%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nikita%22%2C%22lastName%22%3A%22Bibinov%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%20V.%22%2C%22lastName%22%3A%22Blanco%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Pfaender%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sebastian%22%2C%22lastName%22%3A%22Thei%5Cu00df%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Wolter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%5D%2C%22abstractNote%22%3A%22Microorganisms%20pose%20a%20serious%20threat%20for%20us%20humans%2C%20which%20is%20exemplified%20by%20the%20recent%20emergence%20of%20pathogens%20such%20as%20SARS-CoV-2%20or%20the%20increasing%20number%20of%20multi-resistant%20pathogens%20such%20as%20MRSA.%20To%20control%20surface%20microorganisms%20and%20viruses%2C%20we%20investigated%20the%20disinfection%20properties%20of%20an%20AI-controlled%20robot%2C%20HERO21%2C%20equipped%20with%20eight%20130-W%20low%20pressure%20UV-C%20mercury%20vapor%20discharge%20lamps%20emitting%20at%20a%20wavelength%20of%20254%20nm%2C%20which%20is%20strongly%20absorbed%20by%20DNA%20and%20RNA%2C%20thus%20inactivating%20illuminated%20microorganisms.%20Emissivity%20and%20spatial%20irradiance%20distribution%20of%20a%20single%20UV-C%20lamp%20unit%20was%20determined%20using%20a%20calibrated%20spectrometer%20and%20numerical%20simulation%2C%20respectively.%20The%20disinfection%20efficiency%20of%20single%20lamps%20is%20determined%20by%20microbiological%20tests%20using%20B.%20subtilis%20spores%2C%20which%20are%20known%20to%20be%20UV-C%20resistant.%20The%20required%20time%20for%20D99%20disinfection%20and%20the%20corresponding%20UV-C%20irradiance%20dose%20amount%20to%2060%20s%20and%2037.3%20mJ%5Cu2022cm%5Cu2212%202%20at%20a%20distance%20of%201%20m%20to%20the%20Hg-lamp%2C%20respectively.%20Spatially%20resolved%20irradiance%20produced%20by%20a%20disinfection%20unit%20consisting%20of%20eight%20lamps%20is%20calcu%5Cu00ad%20lated%20using%20results%20of%20one%20UV-C%20lamp%20characterization.%20This%20calculation%20shows%20that%20the%20UV-C%20robot%20HERO21%20equipped%20with%20the%20mentioned%20UV-C%20unit%20causes%20an%20irradiance%20at%20%5Cu03bb%3D254%20nm%20of%202.67%20mJ%5Cu2022cm%5Cu2212%202%5Cu2022s%5Cu2212%201%20at%201%20m%20and%200.29%20mJ%5Cu2022cm%5Cu2212%202%5Cu2022s%5Cu2212%201%20at%203%20m%20distances.%20These%20values%20result%20in%20D99%20disinfection%20times%20of%2014%20s%20and%20129%20s%20for%20B.%20subtilis%20spores%2C%20respectively.%20Similarly%2C%20human%20coronavirus%20229E%2C%20structurally%20very%20similar%20to%20SARS-CoV-2%2C%20could%20be%20efficiently%20inactivated%20by%203%5Cu20135%20orders%20of%20magnitude%20within%2010%20-%2030%20s%20exposure%20time%20or%20doses%20of%202%20-%206%20mJ%5Cu2022cm%5Cu2212%202%2C%20respectively.%20In%20conclusion%2C%20with%20the%20development%20of%20the%20HERO21%20disinfection%20robot%2C%20we%20were%20able%20to%20determine%20the%20inactivation%20efficiency%20of%20bacteria%20and%20viruses%20on%20surfaces%20under%20laboratory%20conditions.%22%2C%22date%22%3A%2209%5C%2F2022%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jpap.2022.100123%22%2C%22ISSN%22%3A%2226664690%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flinkinghub.elsevier.com%5C%2Fretrieve%5C%2Fpii%5C%2FS2666469022000161%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222022-11-24T18%3A57%3A06Z%22%7D%7D%2C%7B%22key%22%3A%22GR86ZYKU%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Wollitzer%20et%20al.%22%2C%22parsedDate%22%3A%222021%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWollitzer%2C%20M.%2C%20Armbrecht%2C%20G.%2C%20%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20M.%2C%20Awakowicz%2C%20P.%2C%20Musch%2C%20T.%2C%20Gr%26%23xF6%3Bger%2C%20S.%2C%20Bergner%2C%20A.%2C%20Notzon%2C%20G.%2C%20%26amp%3B%20Van%20Delden%2C%20M.%20%282021%29.%20%3Ci%3EIgnition%20device%20and%20method%20for%20igniting%20an%20air%5C%2Ffuel%20mixture%3C%5C%2Fi%3E.%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DGR86ZYKU%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22patent%22%2C%22title%22%3A%22Ignition%20device%20and%20method%20for%20igniting%20an%20air%5C%2Ffuel%20mixture%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Wollitzer%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gunnar%22%2C%22lastName%22%3A%22Armbrecht%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Musch%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Sven%22%2C%22lastName%22%3A%22Gr%5Cu00f6ger%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Andre%22%2C%22lastName%22%3A%22Bergner%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gordon%22%2C%22lastName%22%3A%22Notzon%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Marcel%22%2C%22lastName%22%3A%22Van%20Delden%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22country%22%3A%22%22%2C%22assignee%22%3A%22%22%2C%22issuingAuthority%22%3A%22%22%2C%22patentNumber%22%3A%22%22%2C%22filingDate%22%3A%22%22%2C%22applicationNumber%22%3A%22%22%2C%22priorityNumbers%22%3A%22%22%2C%22issueDate%22%3A%222021%22%2C%22references%22%3A%22%22%2C%22legalStatus%22%3A%22%22%2C%22language%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T08%3A07%3A25Z%22%7D%7D%2C%7B%22key%22%3A%22URQTI84A%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fuchs%20et%20al.%22%2C%22parsedDate%22%3A%222021%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20M.%2C%20Wollitzer%2C%20M.%2C%20Armbrecht%2C%20G.%2C%20Awakowicz%2C%20P.%2C%20Musch%2C%20T.%2C%20Gr%26%23xF6%3Bger%2C%20S.%2C%20Bergner%2C%20A.%2C%20Notzon%2C%20G.%2C%20%26amp%3B%20Van%20Delden%2C%20M.%20%282021%29.%20%3Ci%3ESpark%20plug%20for%20a%20high%20frequency%20ignition%20system%3C%5C%2Fi%3E.%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DURQTI84A%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22patent%22%2C%22title%22%3A%22Spark%20plug%20for%20a%20high%20frequency%20ignition%20system%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Wollitzer%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gunnar%22%2C%22lastName%22%3A%22Armbrecht%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Musch%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Sven%22%2C%22lastName%22%3A%22Gr%5Cu00f6ger%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Andre%22%2C%22lastName%22%3A%22Bergner%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gordon%22%2C%22lastName%22%3A%22Notzon%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Marcel%22%2C%22lastName%22%3A%22Van%20Delden%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22country%22%3A%22%22%2C%22assignee%22%3A%22%22%2C%22issuingAuthority%22%3A%22%22%2C%22patentNumber%22%3A%22%22%2C%22filingDate%22%3A%22%22%2C%22applicationNumber%22%3A%22%22%2C%22priorityNumbers%22%3A%22%22%2C%22issueDate%22%3A%222021%22%2C%22references%22%3A%22%22%2C%22legalStatus%22%3A%22%22%2C%22language%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T08%3A07%3A25Z%22%7D%7D%2C%7B%22key%22%3A%22SCFK4TVD%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Armbrecht%20et%20al.%22%2C%22parsedDate%22%3A%222021%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EArmbrecht%2C%20G.%2C%20%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20M.%2C%20Wollitzer%2C%20M.%2C%20Van%20Delden%2C%20M.%2C%20Musch%2C%20T.%2C%20Groger%2C%20S.%2C%20Bergner%2C%20A.%2C%20Notzon%2C%20G.%2C%20%26amp%3B%20Awakowicz%2C%20P.%20%282021%29.%20%3Ci%3EIgnition%20device%20for%20igniting%20an%20air%5C%2Ffuel%20mixture%20in%20a%20combustion%20chamber%3C%5C%2Fi%3E.%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DSCFK4TVD%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22patent%22%2C%22title%22%3A%22Ignition%20device%20for%20igniting%20an%20air%5C%2Ffuel%20mixture%20in%20a%20combustion%20chamber%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gunnar%22%2C%22lastName%22%3A%22Armbrecht%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Wollitzer%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Marcel%22%2C%22lastName%22%3A%22Van%20Delden%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Musch%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Sven%22%2C%22lastName%22%3A%22Groger%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Andre%22%2C%22lastName%22%3A%22Bergner%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gordon%22%2C%22lastName%22%3A%22Notzon%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22country%22%3A%22%22%2C%22assignee%22%3A%22%22%2C%22issuingAuthority%22%3A%22%22%2C%22patentNumber%22%3A%22%22%2C%22filingDate%22%3A%22%22%2C%22applicationNumber%22%3A%22%22%2C%22priorityNumbers%22%3A%22%22%2C%22issueDate%22%3A%222021%22%2C%22references%22%3A%22%22%2C%22legalStatus%22%3A%22%22%2C%22language%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T08%3A07%3A25Z%22%7D%7D%2C%7B%22key%22%3A%225Z59ZSDE%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kogelheide%20et%20al.%22%2C%22parsedDate%22%3A%222020-07-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKogelheide%2C%20F.%2C%20Voigt%2C%20F.%2C%20Hillebrand%2C%20B.%2C%20Moeller%2C%20R.%2C%20%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20F.%2C%20Gibson%2C%20A.%20R.%2C%20Awakowicz%2C%20P.%2C%20Stapelmann%2C%20K.%2C%20%26amp%3B%20Fiebrandt%2C%20M.%20%282020%29.%20The%20role%20of%20humidity%20and%20UV-C%20emission%20in%20the%20inactivation%20of%20%3Ci%3EB.%20subtilis%3C%5C%2Fi%3E%20spores%20during%20atmospheric-pressure%20dielectric%20barrier%20discharge%20treatment.%20%3Ci%3EJournal%20of%20Physics%20D%3A%20Applied%20Physics%3C%5C%2Fi%3E%2C%20%3Ci%3E53%3C%5C%2Fi%3E%2829%29%2C%20295201.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1088%5C%2F1361-6463%5C%2Fab77cc%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1088%5C%2F1361-6463%5C%2Fab77cc%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3D5Z59ZSDE%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20role%20of%20humidity%20and%20UV-C%20emission%20in%20the%20inactivation%20of%20%3Ci%3EB.%20subtilis%3C%5C%2Fi%3E%20spores%20during%20atmospheric-pressure%20dielectric%20barrier%20discharge%20treatment%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friederike%22%2C%22lastName%22%3A%22Kogelheide%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Farina%22%2C%22lastName%22%3A%22Voigt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bastian%22%2C%22lastName%22%3A%22Hillebrand%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralf%22%2C%22lastName%22%3A%22Moeller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Felix%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrew%20R.%22%2C%22lastName%22%3A%22Gibson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22Stapelmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcel%22%2C%22lastName%22%3A%22Fiebrandt%22%7D%5D%2C%22abstractNote%22%3A%22Experiments%20are%20performed%20to%20assess%20the%20inactivation%20of%20Bacillus%20subtilis%20spores%20using%20a%20non-thermal%20atmospheric-pressure%20dielectric%20barrier%20discharge.%20The%20plasma%20source%20used%20in%20this%20study%20is%20mounted%20inside%20a%20vacuum%20vessel%20and%20operated%20in%20controlled%20gas%20mixtures.%20In%20this%20context%2C%20spore%20inactivation%20is%20measured%20under%20varying%20nitrogen%5C%2Foxygen%20and%20humidity%20content%20and%20compared%20to%20spore%20inactivation%20using%20ambient%20air.%20Operating%20the%20dielectric%20barrier%20discharge%20in%20a%20sealed%20vessel%20offers%20the%20ability%20to%20distinguish%20between%20possible%20spore%20inactivation%20mechanisms%20since%20different%20process%20gas%20mixtures%20lead%20to%20the%20formation%20of%20distinct%20reactive%20species.%20The%20UV%20irradiance%20and%20the%20ozone%20density%20within%20the%20plasma%20volume%20are%20determined%20applying%20spectroscopic%20diagnostics%20with%20neither%20found%20to%20fully%20correlate%20with%20spore%20inactivation.%20It%20is%20found%20that%20spore%20inactivation%20is%20most%20strongly%20correlated%20with%20the%20humidity%20content%20in%20the%20feed%20gas%2C%20implying%20that%20reactive%20species%20formed%2C%20either%20directly%20or%20indirectly%2C%20from%20water%20molecules%20are%20strong%20mediators%20of%20spore%20inactivation.%22%2C%22date%22%3A%222020-07-15%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1088%5C%2F1361-6463%5C%2Fab77cc%22%2C%22ISSN%22%3A%220022-3727%2C%201361-6463%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fiopscience.iop.org%5C%2Farticle%5C%2F10.1088%5C%2F1361-6463%5C%2Fab77cc%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T14%3A31%3A13Z%22%7D%7D%2C%7B%22key%22%3A%22SIMCQ4IK%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Balzer%20et%20al.%22%2C%22parsedDate%22%3A%222019%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBalzer%2C%20J.%2C%20Demir%2C%20E.%2C%20Kogelheide%2C%20F.%2C%20%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20P.%20C.%2C%20Stapelmann%2C%20K.%2C%20%26amp%3B%20Opl%26%23xE4%3Bnder%2C%20C.%20%282019%29.%20Cold%20atmospheric%20plasma%20%28CAP%29%20differently%20affects%20migration%20and%20differentiation%20of%20keratinocytes%20via%20hydrogen%20peroxide%20and%20nitric%20oxide-related%20products.%20%3Ci%3EClinical%20Plasma%20Medicine%3C%5C%2Fi%3E%2C%20%3Ci%3E13%3C%5C%2Fi%3E%2C%201%26%23x2013%3B8.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cpme.2018.11.001%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cpme.2018.11.001%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DSIMCQ4IK%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cold%20atmospheric%20plasma%20%28CAP%29%20differently%20affects%20migration%20and%20differentiation%20of%20keratinocytes%20via%20hydrogen%20peroxide%20and%20nitric%20oxide-related%20products%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julian%22%2C%22lastName%22%3A%22Balzer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erhan%22%2C%22lastName%22%3A%22Demir%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friederike%22%2C%22lastName%22%3A%22Kogelheide%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%20C.%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22Stapelmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Opl%5Cu00e4nder%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20A%20promising%20approach%20to%20treat%20infected%20chronic%20wounds%20is%20the%20treatment%20with%20%5Cu201ccold%5Cu201d%20atmospheric%20plasma%20%28CAP%29%20that%20has%20a%20broad%20antibacterial%20spectrum%20and%20can%20enhance%20microcirculation.%20Dielectric%20barrier%20discharge%20%28DBD%29%20devices%20generate%20CAP%20containing%20reactive%20species%2C%20leading%20to%20acidi%5Cufb01cation%20and%20the%20accumulation%20of%20hydrogen%20peroxide%20%28H2O2%29%2C%20nitrite%20and%20nitrate%20within%20the%20treated%20tissue%5C%2Fliquids.%5CnObjective%3A%20Since%20CAP%20produced%20species%20may%20a%5Cufb00ect%20wound%20healing%20and%20cell%20behavior%2C%20we%20investigated%20the%20possible%20DBD%5C%2FCAP-induced%20e%5Cufb00ects%20on%20human%20keratinocytes.%5CnMethods%3A%20Primary%20keratinocytes%20were%20treated%20by%20a%20DBD%20device%20%2813.5%20kV%2C%20300%20Hz%3B%200%5Cu2013300%20s%29.%20DBD-induced%20changes%20%28pH%3B%20nitrite%2C%20nitrate%3B%20H2O2%29%20in%20treated%20media%20were%20evaluated.%20As%20control%20and%20to%20investigate%20the%20impact%20of%20the%20CAPproduced%20species%2C%20equivalents%20amounts%20of%20H2O2%2C%20HCL%2C%20nitrite%20and%20nitrate%20as%20obtained%20by%20CAP%20treatments%20%280%2C%2060%2C%20300%20s%29%20were%20added%20separately%20or%20combined%20to%20keratinocytes.%20Cell%20viability%20and%20proliferation%20were%20determined%20by%20live%20cell%20imaging%20and%20a%20resazurin-based%20assay.%20Gap%20closure%20rates%20were%20assessed%20by%20migration%20assays.%20Di%5Cufb00erentiation%5C%2Fproliferation%20states%20were%20determined%20by%20qRT-PCR%20analysis%20of%20KI67%20and%20involucrin.%5CnResults%3A%20We%20found%20that%20even%20longer%20CAP-treatment%20times%20%28300%20s%29%20did%20not%20reduce%20cell%20viability.%20However%2C%20migration%5C%2Fproliferation%20was%20a%5Cufb00ected%20by%20longer%20treatments%20resulting%20in%20a%20delay%20of%20gap%20closure%20in%20migration%20assays.%20The%20mRNA%20expression%20of%20involucrin%20and%20KI67%20showed%20a%20pro-di%5Cufb00erentiation%20e%5Cufb00ect%20induced%20by%20longer%20CAP%20treatment.%20Similar%20e%5Cufb00ects%20could%20be%20induced%20by%20adding%20H2O2%20in%20amounts%20found%20after%20a%20300%20s%20CAP%20treatment.%20The%20e%5Cufb00ects%20were%20reversed%20by%20catalase.%20Shorter%20CAP%20treatment%20%2860%20s%29%20did%20not%20reveal%20pro-di%5Cufb00erentiation%20e%5Cufb00ects%2C%20but%20signi%5Cufb01cantly%20accelerated%20gap%20closure.%20Lower%20H2O2%20concentrations%2C%20equivalent%20to%20a%2060%20s%20CAP%20treatment%2C%20induced%20also%20upregulation%20of%20involucrin%2C%20which%20in%20turn%20could%20be%20diminished%20by%20low%20concentrations%20of%20nitrite%5C%2Fnitrate%2C%20indicating%20a%20potential%20mediation%20of%20H2O2-induced%20e%5Cufb00ects%20by%20parallel%20CAP-induced%20accumulation%20of%20these%20nitric%20oxide%20derivatives.%5CnConclusion%3A%20CAP%20treatment%20theoretically%20could%20kill%20several%20birds%20with%20one%20stone%5Cu2014overcome%20bacterial%20contamination%2C%20improve%20microcirculation%20and%20additionally%20compensate%20missing%20H2O2%20and%20nitric%20oxide%5Cu2014%20facilitating%20wound%20healing.%20However%2C%20clinical%20CAP%20treatment%20must%20be%20well%20balanced%20to%20avoid%20possible%20unwanted%20side%20e%5Cufb00ects%2C%20such%20as%20a%20delayed%20healing%20process%20and%20tissue%20damage.%22%2C%22date%22%3A%2203%5C%2F2019%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.cpme.2018.11.001%22%2C%22ISSN%22%3A%2222128166%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flinkinghub.elsevier.com%5C%2Fretrieve%5C%2Fpii%5C%2FS2212816618300404%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-18T05%3A37%3A22Z%22%7D%7D%2C%7B%22key%22%3A%22ARK6VT5K%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fuchs%20et%20al.%22%2C%22parsedDate%22%3A%222017-11-30%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20F.%20M.%2C%20Raguse%2C%20M.%2C%20Fiebrandt%2C%20M.%2C%20Madela%2C%20K.%2C%20Awakowicz%2C%20P.%2C%20Laue%2C%20M.%2C%20Stapelmann%2C%20K.%2C%20%26amp%3B%20Moeller%2C%20R.%20%282017%29.%20Investigating%20the%20Detrimental%20Effects%20of%20Low%20Pressure%20Plasma%20Sterilization%20on%20the%20Survival%20of%20Bacillus%20subtilis%20Spores%20Using%20Live%20Cell%20Microscopy.%20%3Ci%3EJournal%20of%20Visualized%20Experiments%3C%5C%2Fi%3E%2C%20%3Ci%3E129%3C%5C%2Fi%3E%2C%2056666.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3791%5C%2F56666%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3791%5C%2F56666%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DARK6VT5K%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Investigating%20the%20Detrimental%20Effects%20of%20Low%20Pressure%20Plasma%20Sterilization%20on%20the%20Survival%20of%20Bacillus%20subtilis%20Spores%20Using%20Live%20Cell%20Microscopy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Felix%20M.%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marina%22%2C%22lastName%22%3A%22Raguse%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcel%22%2C%22lastName%22%3A%22Fiebrandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kazimierz%22%2C%22lastName%22%3A%22Madela%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Laue%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22Stapelmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralf%22%2C%22lastName%22%3A%22Moeller%22%7D%5D%2C%22abstractNote%22%3A%22Plasma%20sterilization%20is%20a%20promising%20alternative%20to%20conventional%20sterilization%20methods%20for%20industrial%2C%20clinical%2C%20and%20spaceflight%20purposes.%20Low%20pressure%20plasma%20%28LPP%29%20discharges%20contain%20a%20broad%20spectrum%20of%20active%20species%2C%20which%20lead%20to%20rapid%20microbial%20inactivation.%20To%20study%20the%20efficiency%20and%20mechanisms%20of%20sterilization%20by%20LPP%2C%20we%20use%20spores%20of%20the%20test%20organism%20Bacillus%20subtilis%20because%20of%20their%20extraordinary%20resistance%20against%20conventional%20sterilization%20procedures.%20We%20describe%20the%20production%20of%20B.%20subtilis%20spore%20monolayers%2C%20the%20sterilization%20process%20by%20low%20pressure%20plasma%20in%20a%20double%20inductively%20coupled%20plasma%20reactor%2C%20the%20characterization%20of%20spore%20morphology%20using%20scanning%20electron%20microscopy%20%28SEM%29%2C%20and%20the%20analysis%20of%20germination%20and%20outgrowth%20of%20spores%20by%20live%20cell%20microscopy.%20A%20major%20target%20of%20plasma%20species%20is%20genomic%20material%20%28DNA%29%20and%20repair%20of%20plasma-induced%20DNA%20lesions%20upon%20spore%20revival%20is%20crucial%20for%20survival%20of%20the%20organism.%20Here%2C%20we%20study%20the%20germination%20capacity%20of%20spores%20and%20the%20role%20of%20DNA%20repair%20during%20spore%20germination%20and%20outgrowth%20after%20treatment%20with%20LPP%20by%20tracking%20fluorescently-labelled%20DNA%20repair%20proteins%20%28RecA%29%20with%20time-resolved%20confocal%20fluorescence%20microscopy.%20Treated%20and%20untreated%20spore%20monolayers%20are%20activated%20for%20germination%20and%20visualized%20with%20an%20inverted%20confocal%20live%20cell%20microscope%20over%20time%20to%20follow%20the%20reaction%20of%20individual%20spores.%20Our%20observations%20reveal%20that%20the%20fraction%20of%20germinating%20and%20outgrowing%20spores%20is%20dependent%20on%20the%20duration%20of%20LPP-treatment%20reaching%20a%20minimum%20after%20120%20s.%20RecA-YFP%20%28yellow%20fluorescence%20protein%29%20fluorescence%20was%20detected%20only%20in%20few%20spores%20and%20developed%20in%20all%20outgrowing%20cells%20with%20a%20slight%20elevation%20in%20LPP-treated%20spores.%20Moreover%2C%20some%20of%20the%20vegetative%20bacteria%20derived%20from%20LPP-treated%20spores%20showed%20an%20increase%20in%20cytoplasm%20and%20tended%20to%20lyse.%20The%20described%20methods%20for%20analysis%20of%20individual%20spores%20could%20be%20exemplary%20for%20the%20study%20of%20other%20aspects%20of%20spore%20germination%20and%20outgrowth.%22%2C%22date%22%3A%222017-11-30%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3791%5C%2F56666%22%2C%22ISSN%22%3A%221940-087X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.jove.com%5C%2Fvideo%5C%2F56666%5C%2Finvestigating-detrimental-effects-low-pressure-plasma-sterilization%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T14%3A30%3A44Z%22%7D%7D%2C%7B%22key%22%3A%22FUZ33GQE%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Armbrecht%20et%20al.%22%2C%22parsedDate%22%3A%222017-11-23%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EArmbrecht%2C%20G.%2C%20Awakowicz%2C%20P.%2C%20Bergner%2C%20A.%2C%20Delden%2C%20M.%20van%2C%20%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20M.%2C%20Gr%26%23xF6%3Bger%2C%20S.%2C%20Musch%2C%20T.%2C%20Notzon%2C%20G.%2C%20%26amp%3B%20Wollitzer%2C%20M.%20%282017%29.%20%3Ci%3EZ%26%23xFC%3Bndkerze%20f%26%23xFC%3Br%20eine%20Hochfrequenz-Z%26%23xFC%3Bndanlage%3C%5C%2Fi%3E%20%28Patent%20No.%20DE102016006350A1%29.%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DFUZ33GQE%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22patent%22%2C%22title%22%3A%22Z%5Cu00fcndkerze%20f%5Cu00fcr%20eine%20Hochfrequenz-Z%5Cu00fcndanlage%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gunnar%22%2C%22lastName%22%3A%22Armbrecht%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Andre%22%2C%22lastName%22%3A%22Bergner%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Marcel%20van%22%2C%22lastName%22%3A%22Delden%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Sven%22%2C%22lastName%22%3A%22Gr%5Cu00f6ger%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Musch%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gordon%22%2C%22lastName%22%3A%22Notzon%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Wollitzer%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22country%22%3A%22DE%22%2C%22assignee%22%3A%22ROSENBERGER%20Hochfrequenztechnik%20GmbH%20%26Co.%20KG%2C%2083413%2C%20Fridolfing%2C%20DE%22%2C%22issuingAuthority%22%3A%22%22%2C%22patentNumber%22%3A%22DE102016006350A1%22%2C%22filingDate%22%3A%2223.05.2016%22%2C%22applicationNumber%22%3A%22%22%2C%22priorityNumbers%22%3A%22%22%2C%22issueDate%22%3A%2223.11.2017%22%2C%22references%22%3A%22%22%2C%22legalStatus%22%3A%22%22%2C%22language%22%3A%22de%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T08%3A07%3A25Z%22%7D%7D%2C%7B%22key%22%3A%22XXKZCS8E%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Armbrecht%20et%20al.%22%2C%22parsedDate%22%3A%222017-07-12%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EArmbrecht%2C%20G.%2C%20Awakowicz%2C%20P.%2C%20Bergner%2C%20A.%2C%20Delden%2C%20M.%20van%2C%20%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20M.%2C%20Gr%26%23xF6%3Bger%2C%20S.%2C%20Musch%2C%20T.%2C%20Notzon%2C%20G.%2C%20%26amp%3B%20Wollitzer%2C%20M.%20%282017%29.%20%3Ci%3EZ%26%23xFC%3Bndvorrichtung%20und%20Verfahren%20zum%20Z%26%23xFC%3Bnden%20eines%20Luft-Kraftstoffgemisches%3C%5C%2Fi%3E%20%28Patent%20No.%20DE102016006782A1%29.%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DXXKZCS8E%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22patent%22%2C%22title%22%3A%22Z%5Cu00fcndvorrichtung%20und%20Verfahren%20zum%20Z%5Cu00fcnden%20eines%20Luft-Kraftstoffgemisches%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gunnar%22%2C%22lastName%22%3A%22Armbrecht%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Andre%22%2C%22lastName%22%3A%22Bergner%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Marcel%20van%22%2C%22lastName%22%3A%22Delden%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Sven%22%2C%22lastName%22%3A%22Gr%5Cu00f6ger%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Musch%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Gordon%22%2C%22lastName%22%3A%22Notzon%22%7D%2C%7B%22creatorType%22%3A%22inventor%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Wollitzer%22%7D%5D%2C%22abstractNote%22%3A%22Die%20vorliegende%20Erfindung%20betrifft%20eine%20Z%5Cu00fcndvorrichtung%20zum%20Z%5Cu00fcnden%20eines%20Luft-Kraftstoffgemisches%20in%20mindestens%20einem%20Brennraum%2C%20insbesondere%20einer%20Brennkraftmaschine%2C%20mit%20mindestens%20einem%20Z%5Cu00fcndsystem%20mit%20Elektroden%20f%5Cu00fcr%20jeden%20Brennraum%2C%20mindestens%20einer%20Hochspannungsquelle%20zum%20Erzeugen%20eines%20elektrischen%20Hochspannungsimpulses%20an%20einem%20Ausgang%20der%20Hochspannungsquelle%20und%20mit%20mindestens%20einer%20Hochfrequenzspannungsquelle%20zum%20Erzeugen%20einer%20elektrischen%20Hochfrequenz-Wechselspannung%20an%20einem%20Ausgang%20der%20Hochfrequenzspannungsquelle%2C%20wobei%20m%20Z%5Cu00fcndsysteme%20%2810i%29%20mit%20m%20%5Cu2208%20N%20%28nat%5Cu00fcrliche%20Zahlen%20ohne%20Null%29%20sowie%20m%20%5Cu2265%202%2C%20vorgesehen%20sind%2C%20wobei%20k%20Hochfrequenzspannungsquellen%20mit%20k%20%5Cu2208%20N%2C%20sowie%20k%20%3C%20m%20vorgesehen%20sind%2C%20wobei%20mindestens%20eine%20Leistungsverteiler-Vorrichtung%20vorgesehen%20ist%2C%20welche%20einerseits%20mit%20mindestens%20einer%20Hochfrequenzspannungsquelle%20und%20andererseits%20mit%20n%20Z%5Cu00fcndsystemen%2C%20wobei%20n%20%5Cu2208%20N%20sowie%202%20%5Cu2264%20n%20%5Cu2264%20m%2C%20elektrisch%20verbunden%20ist%2C%20wobei%20die%20Leistungsverteiler-Vorrichtung%20die%20Hochfrequenz-Wechselspannung%20bzw.%20-spannungen%20aus%20der%20bzw.%20aus%20den%20mit%20dieser%20Leistungsverteiler-Vorrichtung%20elektrisch%20verbundenen%20Hochfrequenzspannungsquelle%20bzw.%20-quellen%20an%20die%20mit%20dieser%20Leistungsverteiler-Vorrichtung%20elektrisch%20verbundenen%20n%20Z%5Cu00fcndsysteme%20%5Cu00fcbertr%5Cu00e4gt.%22%2C%22country%22%3A%22DE%22%2C%22assignee%22%3A%22ROSENBERGER%20Hochfrequenztechnik%20GmbH%20%26Co.%20KG%2C%2083413%2C%20Fridolfing%2C%20DE%22%2C%22issuingAuthority%22%3A%22%22%2C%22patentNumber%22%3A%22DE102016006782A1%22%2C%22filingDate%22%3A%2202.06.2016%22%2C%22applicationNumber%22%3A%22%22%2C%22priorityNumbers%22%3A%22%22%2C%22issueDate%22%3A%2207.12.2017%22%2C%22references%22%3A%22%22%2C%22legalStatus%22%3A%22%22%2C%22language%22%3A%22de%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T08%3A07%3A25Z%22%7D%7D%2C%7B%22key%22%3A%22YJ99IT3A%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Balzer%20et%20al.%22%2C%22parsedDate%22%3A%222015-12-14%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBalzer%2C%20J.%2C%20Heuer%2C%20K.%2C%20Demir%2C%20E.%2C%20Hoffmanns%2C%20M.%20A.%2C%20Baldus%2C%20S.%2C%20%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20P.%20C.%2C%20Awakowicz%2C%20P.%2C%20Suschek%2C%20C.%20V.%2C%20%26amp%3B%20Opl%26%23xE4%3Bnder%2C%20C.%20%282015%29.%20Non-Thermal%20Dielectric%20Barrier%20Discharge%20%28DBD%29%20Effects%20on%20Proliferation%20and%20Differentiation%20of%20Human%20Fibroblasts%20Are%20Primary%20Mediated%20by%20Hydrogen%20Peroxide.%20%3Ci%3EPLOS%20ONE%3C%5C%2Fi%3E%2C%20%3Ci%3E10%3C%5C%2Fi%3E%2812%29%2C%20e0144968.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0144968%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0144968%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DYJ99IT3A%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Non-Thermal%20Dielectric%20Barrier%20Discharge%20%28DBD%29%20Effects%20on%20Proliferation%20and%20Differentiation%20of%20Human%20Fibroblasts%20Are%20Primary%20Mediated%20by%20Hydrogen%20Peroxide%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julian%22%2C%22lastName%22%3A%22Balzer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kiara%22%2C%22lastName%22%3A%22Heuer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erhan%22%2C%22lastName%22%3A%22Demir%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%20A.%22%2C%22lastName%22%3A%22Hoffmanns%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sabrina%22%2C%22lastName%22%3A%22Baldus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%20C.%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%20V.%22%2C%22lastName%22%3A%22Suschek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Opl%5Cu00e4nder%22%7D%2C%7B%22creatorType%22%3A%22editor%22%2C%22firstName%22%3A%22Mohammed%22%2C%22lastName%22%3A%22Yousfi%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222015-12-14%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0144968%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdx.plos.org%5C%2F10.1371%5C%2Fjournal.pone.0144968%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T14%3A23%3A22Z%22%7D%7D%2C%7B%22key%22%3A%22YCHN8CXR%22%2C%22library%22%3A%7B%22id%22%3A2825793%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Heuer%20et%20al.%22%2C%22parsedDate%22%3A%222015%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHeuer%2C%20K.%2C%20Hoffmanns%2C%20M.%20A.%2C%20Demir%2C%20E.%2C%20Baldus%2C%20S.%2C%20Volkmar%2C%20C.%20M.%2C%20R%26%23xF6%3Bhle%2C%20M.%2C%20%3Cstrong%3EFuchs%3C%5C%2Fstrong%3E%2C%20P.%20C.%2C%20Awakowicz%2C%20P.%2C%20Suschek%2C%20C.%20V.%2C%20%26amp%3B%20Opl%26%23xE4%3Bnder%2C%20C.%20%282015%29.%20The%20topical%20use%20of%20non-thermal%20dielectric%20barrier%20discharge%20%28DBD%29%3A%20Nitric%20oxide%20related%20effects%20on%20human%20skin.%20%3Ci%3ENitric%20Oxide%3C%5C%2Fi%3E%2C%20%3Ci%3E44%3C%5C%2Fi%3E%2C%2052%26%23x2013%3B60.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.niox.2014.11.015%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.niox.2014.11.015%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.aept.ruhr-uni-bochum.de%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D2825793%26amp%3Bitem_key%3DYCHN8CXR%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20topical%20use%20of%20non-thermal%20dielectric%20barrier%20discharge%20%28DBD%29%3A%20Nitric%20oxide%20related%20effects%20on%20human%20skin%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kiara%22%2C%22lastName%22%3A%22Heuer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%20A.%22%2C%22lastName%22%3A%22Hoffmanns%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erhan%22%2C%22lastName%22%3A%22Demir%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sabrina%22%2C%22lastName%22%3A%22Baldus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%20M.%22%2C%22lastName%22%3A%22Volkmar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirco%22%2C%22lastName%22%3A%22R%5Cu00f6hle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%20C.%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Awakowicz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%20V.%22%2C%22lastName%22%3A%22Suschek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Opl%5Cu00e4nder%22%7D%5D%2C%22abstractNote%22%3A%22Dielectric%20barrier%20discharge%20%28DBD%29%20devices%20generate%20air%20plasma%20above%20the%20skin%20containing%20active%20and%20reactive%20species%20including%20nitric%20oxide%20%28NO%29.%20Since%20NO%20plays%20an%20essential%20role%20in%20skin%20physiology%2C%20a%20topical%20application%20of%20NO%20by%20plasma%20may%20be%20useful%20in%20the%20treatment%20of%20skin%20infections%2C%20impaired%20microcirculation%20and%20wound%20healing.%22%2C%22date%22%3A%2201%5C%2F2015%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.niox.2014.11.015%22%2C%22ISSN%22%3A%2210898603%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flinkinghub.elsevier.com%5C%2Fretrieve%5C%2Fpii%5C%2FS1089860314005059%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-07-19T14%3A27%3A22Z%22%7D%7D%5D%7D
Fuchs, F., Bibinov, N., Blanco, E. V., Pfaender, S., Theiß, S., Wolter, H., & Awakowicz, P. (2022). Characterization of a robot-assisted UV-C disinfection for the inactivation of surface-associated microorganisms and viruses. Journal of Photochemistry and Photobiology, 11, 100123. https://doi.org/10.1016/j.jpap.2022.100123 Cite
Wollitzer, M., Armbrecht, G., Fuchs, M., Awakowicz, P., Musch, T., Gröger, S., Bergner, A., Notzon, G., & Van Delden, M. (2021). Ignition device and method for igniting an air/fuel mixture. Cite
Fuchs, M., Wollitzer, M., Armbrecht, G., Awakowicz, P., Musch, T., Gröger, S., Bergner, A., Notzon, G., & Van Delden, M. (2021). Spark plug for a high frequency ignition system. Cite
Armbrecht, G., Fuchs, M., Wollitzer, M., Van Delden, M., Musch, T., Groger, S., Bergner, A., Notzon, G., & Awakowicz, P. (2021). Ignition device for igniting an air/fuel mixture in a combustion chamber. Cite
Kogelheide, F., Voigt, F., Hillebrand, B., Moeller, R., Fuchs, F., Gibson, A. R., Awakowicz, P., Stapelmann, K., & Fiebrandt, M. (2020). The role of humidity and UV-C emission in the inactivation of B. subtilis spores during atmospheric-pressure dielectric barrier discharge treatment. Journal of Physics D: Applied Physics, 53(29), 295201. https://doi.org/10.1088/1361-6463/ab77cc Cite
Balzer, J., Demir, E., Kogelheide, F., Fuchs, P. C., Stapelmann, K., & Opländer, C. (2019). Cold atmospheric plasma (CAP) differently affects migration and differentiation of keratinocytes via hydrogen peroxide and nitric oxide-related products. Clinical Plasma Medicine, 13, 1–8. https://doi.org/10.1016/j.cpme.2018.11.001 Cite
Fuchs, F. M., Raguse, M., Fiebrandt, M., Madela, K., Awakowicz, P., Laue, M., Stapelmann, K., & Moeller, R. (2017). Investigating the Detrimental Effects of Low Pressure Plasma Sterilization on the Survival of Bacillus subtilis Spores Using Live Cell Microscopy. Journal of Visualized Experiments, 129, 56666. https://doi.org/10.3791/56666 Cite
Armbrecht, G., Awakowicz, P., Bergner, A., Delden, M. van, Fuchs, M., Gröger, S., Musch, T., Notzon, G., & Wollitzer, M. (2017). Zündkerze für eine Hochfrequenz-Zündanlage (Patent No. DE102016006350A1). Cite
Armbrecht, G., Awakowicz, P., Bergner, A., Delden, M. van, Fuchs, M., Gröger, S., Musch, T., Notzon, G., & Wollitzer, M. (2017). Zündvorrichtung und Verfahren zum Zünden eines Luft-Kraftstoffgemisches (Patent No. DE102016006782A1). Cite
Balzer, J., Heuer, K., Demir, E., Hoffmanns, M. A., Baldus, S., Fuchs, P. C., Awakowicz, P., Suschek, C. V., & Opländer, C. (2015). Non-Thermal Dielectric Barrier Discharge (DBD) Effects on Proliferation and Differentiation of Human Fibroblasts Are Primary Mediated by Hydrogen Peroxide. PLOS ONE, 10(12), e0144968. https://doi.org/10.1371/journal.pone.0144968 Cite
Heuer, K., Hoffmanns, M. A., Demir, E., Baldus, S., Volkmar, C. M., Röhle, M., Fuchs, P. C., Awakowicz, P., Suschek, C. V., & Opländer, C. (2015). The topical use of non-thermal dielectric barrier discharge (DBD): Nitric oxide related effects on human skin. Nitric Oxide, 44, 52–60. https://doi.org/10.1016/j.niox.2014.11.015 Cite